Investigation into the role of MicroRNA in bladder cancer.

Microrna Phd Thesis

These miRNAs will be the focus of this Ph.D. thesis. The discovery of miRNAs In 1981 it was shown that a mutation in the abnormal cell lineage-4 (lin-4) gene interferes with the developmental pattern of the nematode Ceanorhabditis elegans (C. elegans) (Chalfie et al., 1981). Six years later the lin-4 gene product was found to act as a negative regulator of lin-14 whose activity is required for.

Microrna Phd Thesis

Coronary heart disease is a major cause of morbidity and mortality worldwide. Percutaneous coronary intervention (PCI) has become the most widely used method of coronary artery revascularisation. The use of stents to hold open atherosclerosis induced arterial narrowing has significantly reduced elastic recoil and acute vessel occlusion following balloon angioplasty.

Microrna Phd Thesis

Abstract. Haemonchus contortus is one of the most pathogenic nematodes of small ruminants, particularly sheep, and has a major impact on welfare as well as causing significant eco.

Microrna Phd Thesis

All PhD students have an assigned principal supervisor, second scientific supervisor(s), pastoral academic supervisor and a member of the PG committee; these comprising the members of the Thesis Committee’ (TC) responsible for monitoring scholar progress. Formal assessment procedures entail: (i) Week 10 - By this stage, the scholar will be expected to have made some progress on understanding.

Microrna Phd Thesis

Title: Functional analysis of microrna-181a: Identification of target proteins and Application in hcc therapy Thesis (PhD and DIC) - Department of Bioengineering, Imperial College London, 2014. Thompson, Simon Title: The Central Tendon of the Supraspinatus: Structure and Biomechanics Thesis (PhD and DIC) - Department of Bioengineering, Imperial College London, 2014. van Schaik, Tempest Title.

Microrna Phd Thesis

Publications and Presentations related to Thesis - vii - 10. Abdullah Ely, Tanusha Naidoo, Steven M. Mufamadi, Carol Crowther and Patrick B. Arbuthnot. MicroRNA-like hairpin sequences capable of inhibiting HBV replication efficiently in vitro and in vivo. ASGT 10th Annual Meeting, 2007 May 30 - June 3, Washington, USA. 11. Abdullah Ely, Tanusha.

Microrna Phd Thesis

The studies presented in this thesis help further elucidate the active role that miRNA play in retinal degenerations and investigate their potential for use as therapeutics in the retina. In this thesis, I have characterised miRNA involved in the degenerating retina using a sterile model of retinal inflammation, the photo-oxidative damage model, and use this model for investigating the use of.

Microrna Phd Thesis

Characterization of Altered MicroRNA Expression in Cervical Cancer Christine How Doctor of Philosophy Graduate Department of Medical Biophysics University of Toronto 2013 Abstract Cervical cancer is the third most common cancer among women worldwide, and the fourth leading cause of cancer mortality. Despite significant declines in the incidence and mortality rates of cervical cancer in Canada.

Microrna Phd Thesis

BRCA-1 Associated Protein 1 (BAP1) is a nuclear deubiquitylase (DUB) frequently inactivated by mutation in specific cancers including malignant pleural mesothelioma (MPM). Mutations cause loss of nuclear BAP1 expression or catalytic inactivation and, as BAP1 regulates both ubiquitylation and transcription, its loss in cancer may dysregulate expression of specific proteins, and potentially non.

Microrna Phd Thesis

This thesis examines the role of microRNAs in renal fibrosis. MicroRNAs constitute a large family of approximately 22-nucleotide-long non-coding RNAs, that in animal cells regulate gene expression posttranscriptionally. At the start of the project, microRNAs were emerging as potentially important factors in various physiological and pathological processes however, there was very little known.

Microrna Phd Thesis

Butt, Z (2018) Elucidating BAP1-microRNA regulatory networks in mesothelioma. PhD thesis, University of Liverpool. Clement, M (2018) An investigation of emerging signature pedagogy for social entrepreneurship and the sharing of practice. Doctor of Education thesis, University of Liverpool. Blamire, J (2018) The Politics of Anti-Austerity in Liverpool: A More-than-Cuts Approach. PhD thesis.

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