All PhD students have an assigned principal supervisor, second scientific supervisor(s), pastoral academic supervisor and a member of the PG committee; these comprising the members of the Thesis Committee’ (TC) responsible for monitoring scholar progress. Formal assessment procedures entail: (i) Week 10 - By this stage, the scholar will be expected to have made some progress on understanding.
Title: Functional analysis of microrna-181a: Identification of target proteins and Application in hcc therapy Thesis (PhD and DIC) - Department of Bioengineering, Imperial College London, 2014. Thompson, Simon Title: The Central Tendon of the Supraspinatus: Structure and Biomechanics Thesis (PhD and DIC) - Department of Bioengineering, Imperial College London, 2014. van Schaik, Tempest Title.
Publications and Presentations related to Thesis - vii - 10. Abdullah Ely, Tanusha Naidoo, Steven M. Mufamadi, Carol Crowther and Patrick B. Arbuthnot. MicroRNA-like hairpin sequences capable of inhibiting HBV replication efficiently in vitro and in vivo. ASGT 10th Annual Meeting, 2007 May 30 - June 3, Washington, USA. 11. Abdullah Ely, Tanusha.
The studies presented in this thesis help further elucidate the active role that miRNA play in retinal degenerations and investigate their potential for use as therapeutics in the retina. In this thesis, I have characterised miRNA involved in the degenerating retina using a sterile model of retinal inflammation, the photo-oxidative damage model, and use this model for investigating the use of.
Characterization of Altered MicroRNA Expression in Cervical Cancer Christine How Doctor of Philosophy Graduate Department of Medical Biophysics University of Toronto 2013 Abstract Cervical cancer is the third most common cancer among women worldwide, and the fourth leading cause of cancer mortality. Despite significant declines in the incidence and mortality rates of cervical cancer in Canada.
BRCA-1 Associated Protein 1 (BAP1) is a nuclear deubiquitylase (DUB) frequently inactivated by mutation in specific cancers including malignant pleural mesothelioma (MPM). Mutations cause loss of nuclear BAP1 expression or catalytic inactivation and, as BAP1 regulates both ubiquitylation and transcription, its loss in cancer may dysregulate expression of specific proteins, and potentially non.
This thesis examines the role of microRNAs in renal fibrosis. MicroRNAs constitute a large family of approximately 22-nucleotide-long non-coding RNAs, that in animal cells regulate gene expression posttranscriptionally. At the start of the project, microRNAs were emerging as potentially important factors in various physiological and pathological processes however, there was very little known.
Butt, Z (2018) Elucidating BAP1-microRNA regulatory networks in mesothelioma. PhD thesis, University of Liverpool. Clement, M (2018) An investigation of emerging signature pedagogy for social entrepreneurship and the sharing of practice. Doctor of Education thesis, University of Liverpool. Blamire, J (2018) The Politics of Anti-Austerity in Liverpool: A More-than-Cuts Approach. PhD thesis.